Ismael Ayala-Uribe, a 39-year-old Mexican national and former DACA recipient, died in ICE custody after being held at the Adelanto ICE Processing Center in California. He was arrested by ICE and Border Patrol agents on August 17, 2025, during an enforcement operation at a car wash in Fountain Valley, and transferred to Adelanto five days later. During roughly five weeks in detention, he reported severe pain from an infected abscess along with cough, fever, and shaking; on September 18, facility medical staff responded to his complaints with only Tylenol. After developing complications, he was transferred to Victor Valley Global Medical Center, where he was found unresponsive at 1:48 a.m. on September 22 and declared dead at 2:32 a.m. from cardiac arrest arising from septic shock. His family was not notified of his hospitalization until after his death. His death occurred amid a rise in ICE detainee deaths, with at least 16 recorded in nine months of 2025.